User:Mr. Ibrahem/Lisinopril/hydrochlorothiazide

Lisinopril/hydrochlorothiazide, sold under the trade name Zestoretic among others, is a combination of the medications lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic. It is used to treat high blood pressure. Typically, it becomes an option once a person is doing well on the individual components. It is taken by mouth.

Common side effects include dizziness, headache, cough, and feeling tired. Severe side effects may include angioedema and low blood pressure. Use during pregnancy may harm the baby.

The combination was approved for medical use in the United States in 1989. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In the United States the wholesale cost per dose is less than US$0.05. In the United Kingdom it costs the NHS about GB£0.40 per dose. In 2017, it was the 44th most commonly prescribed medication in the United States, with more than 16 million prescriptions.