User:Mr. Ibrahem/Lofexidine

Lofexidine, sold under the brand name Lucemyra among others, is a medication used to treat opioid withdrawal. It is not as effective as buprenorphine. It is taken by mouth. It may be used for up to two weeks and should be stopped gradually.

Common side effects include trouble sleeping, low blood pressure with standing, slow heart rate, sleepiness, and dry mouth. Other side effects may include QT prolongation. Use in pregnancy is of unclear safety. It is an α2 adrenergic receptor agonist.

Lofexidine was approved for use medical use in the United States in 2018. In the United States 84 tablets of 0.18 mg costs about 1,700 USD as of 2021. The similar medication clonidine costs less than 10 USD. It is not commercially available in the United Kingdom as of 2021.