User:Mr. Ibrahem/Lomitapide

Lomitapide, sold under the brand name Juxtapid and Lojuxta , is a medication used to treat homozygous familial hypercholesterolemia (HoFH). It is used together with diet and other measures. Effects related to life expectancy and heart disease are unclear. It is taken by mouth.

Common side effects include diarrhea, nausea, heartburn, abdominal pain, and increased intestinal gas. Serious side effects may include liver problems and fat soluble vitamin deficiency. Use in pregnancy may harm the baby. It works by blocking microsomal triglyceride transfer protein.

Lomitapide was approved for medical use in the United States in 2012 and Europe in 2013. In the United Kingdom a dose of 20 mg per day costs the NHS about £17,800 for 4 weeks as of 2021. This amount in the United States costs about 48,600 USD.