User:Mr. Ibrahem/Lonafarnib

Lonafarnib, sold under the brand name Zokinvy, is a medication used to treat Hutchinson-Gilford progeria syndrome and certain processing-deficient progeroid laminopathies. It is used in people starting at a year old. It is taken by mouth.

Common side effects included nausea, headache, diarrhea, infection, muscle pain, electrolyte problems, weight loss, bone marrow suppression, liver inflammation, high blood pressure, and tiredness. Other side effects may include kidney problems, vision problems, and decreased fertility. Use during pregnancy may harm the baby. It is a farnesyltransferase inhibitor.

Lonafarnib was approved for medical use in the United States in 2020 and Europe in 2022. In the United States, at the initial dose of 50 mg twice per day, it costs about 50,000 USD per month as of 2022.