User:Mr. Ibrahem/Loncastuximab tesirine

Loncastuximab tesirine, sold under the brand name Zynlonta, is a medication used to treat large B-cell lymphoma. It is used when other treatments have failed. It is given by injection into a vein.

Common side effects include low platelets, liver inflammation, low white blood cells, low red blood cells, high blood sugar, rash, swelling, and nausea. Other side effects may include infection. Use in pregnancy may harm the baby. It is an antibody-drug conjugate composed of a monoclonal antibody targeting the protein CD19 attached to an alkylating agent.

Loncastuximab tesirine was approved for medical use in the United States in 2021. As of 2022 it is not yet approved in the United Kingdom or Europe. In the United States it costs about 25,500 USD per 10 mg vial as of 2022.