User:Mr. Ibrahem/Lubiprostone

Lubiprostone, sold under the trade name Amitiza among others, is a medication used to treat chronic constipation of unknown cause and irritable bowel syndrome associated constipation. It is taken by mouth.

Common side effects include nausea, diarrhea, abdominal pain, swelling, and tiredness. Other side effects may include shortness of breath. Safety in pregnancy is unclear. It works by activating certain chloride channels in the intestines which increases fluid release.

Lubiprostone was approved for medical use in the United States in 2006 and Canada in 2015. In the United States a month of medication costs about 290 USD as of 2021. A generic version was approved in 2021 in the USA. It is not commercially available in the United Kingdom.