User:Mr. Ibrahem/Lung cancer

Lung cancer, also known as lung carcinoma, is a cancerous lung tumor characterized by uncontrolled cell growth in tissues of the lung. This growth can spread beyond the lung by the process of metastasis into nearby tissue or other parts of the body. Most cancers that start in the lung, known as primary lung cancers, are carcinomas. The two main types are small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC). The most common symptoms are coughing (including coughing up blood), weight loss, shortness of breath, and chest pains.

The vast majority (>80%) of cases of lung cancer are due to long-term tobacco smoking. Globally, lung cancer in people who have never smoked is increasing. These cases are often caused by a combination of genetic factors and exposure to radon gas, asbestos, second-hand smoke, or other forms of air pollution. Lung cancer may be seen on chest radiographs and computed tomography (CT) scans. The diagnosis is confirmed by biopsy which is usually performed by bronchoscopy or CT-guidance.

Avoidance of risk factors, including smoking and air pollution, is the primary method of prevention. Treatment and long-term outcomes depend on the type of cancer, the stage (degree of spread), and the person's overall health. Most cases are not curable. Common treatments include surgery, chemotherapy, and radiotherapy. NSCLC is sometimes treated with surgery, whereas SCLC usually responds better to chemotherapy and radiotherapy.

Worldwide in 2020, lung cancer occurred in 2.2 million people and resulted in 1.8 million deaths. This makes it the most common cause of cancer-related death in men and second most common in women after breast cancer. Despite the general decline in rates, the rate in people who have never smoked varies between nations, but has generally been increasing, with 15–20% of men being non-smokers and over 50% of women being non-smokers. The most common age at diagnosis is 70 years. In most countries the five-year survival rate is around 10 to 20%, while in Japan it is 33%, in Israel 27%, and in the Republic of Korea 25%. Outcomes on average are worse in the developing world. The first review article about lung cancers, published in 1912 by Isaac Adler, suggested it was underdiagnosed.