User:Mr. Ibrahem/Macitentan

Macitentan, sold under the brand name Opsumit, is a medication used to treat pulmonary arterial hypertension (PAH). It may be used alone or with PDE5 inhibitors or prostanoids. It is taken by mouth.

Common side effects include low red blood cells, headache, and sore throat. Other side effects include liver problems, infertility, and pulmonary edema. Use in pregnancy may harm the baby. It is an endothelin receptor antagonist (ERA) which help widen widen the arteries in the lungs.

Macitentan was approved for medical use in the United States and Europe in 2013. Approval for a generic version was granted in 2021. In the United Kingdom a month of medication costs the NHS about £2,300 as of 2021. In the United States this amount costs about 11,000 USD.