User:Mr. Ibrahem/Methylergometrine

Methylergometrine, sold under the brand name Methergine among others, is a medication used to treat post partum bleeding due to poor uterine contraction. It is less preferred to oxytocin for this use. It has also been used to check if people have angina due to coronary vasospasms. It is used by injection into a muscle, by mouth, or less commonly by injection into a vein.

Common side effects include high blood pressure, seizures, headache, nausea, and low blood pressure. Other side effects may include ringing in the ears, numbness, confusion, and chest pain. Caution is advised in those who have liver problems, kidney problems, or poor blood flow. Safety in pregnancy or breastfeeding is unclear and thus in these situations use is not advised. It is in the family of medicines known as oxytocics and ergot alkaloids.

Methylergometrine is derived from ergometrine which was initially isolated from the fungus Claviceps purpurea in 1935. It is on the World Health Organization's List of Essential Medicines as an alternative to ergometrine. In the United States it is available as a generic medication and costs about 68 USD for 6 tablets of 0.2 mg as of 2020. In the developing world this amount costs about 0.13 USD as of 2015 while the injectable form is about 0.18 USD per dose.