User:Mr. Ibrahem/Methylnaltrexone

Methylnaltrexone (MNTX), sold under the brand name Relistor, is a medication used to treat constipation due to opioids. It may be used when other laxatives are not effective. It is taken by mouth or by injection under the skin.

Common side effects include abdominal pain, diarrhea, dizziness, nausea, and opioid withdrawal. Other side effects may include gastrointestinal perforation. It a peripherally acting μ-opioid receptor antagonist, which means it does not generally affect the central pain reducing effects of other opioids.

Methylnaltrexone was approved for medical use in the United States in 2008. In the United Kingdom the injectable formulation costs the NHS about £21 per dose as of 2021. In the United States this amount costs about 150 USD.