User:Mr. Ibrahem/Mifepristone/misoprostol

Mifepristone/misoprostol, also known as Mifeprex/Cytotec, are two medications packaged together and primarily used to bring about medical abortion. It is a common method of abortions up to 11 weeks of pregnancy; though may also be used in the second trimester. They can also be used for early pregnancy loss up to 12 weeks. Pregnancy testing or ultrasound can confirm success. They may be taken by mouth or placed under the tongue. Use in the first trimester can generally take place at home and can be prescribed by a family doctor, including by telehealth; while in the second trimester hospitalization is recommended.

Side effects may include nausea, upset stomach, and mild fever. Uterine cramps and vaginal bleeding are expected. Heavy bleeding, ongoing pregnancy, and infection may rarely occur. It does not affect the risk of mental health problems, breast cancer, or infertility. It contains mifepristone, a progesterone receptor antagonist which results in breakdown of the decidua; and misoprostol, a prostaglandin E1 that results in cervical ripening and uterine contractions.

Mifepristone came into use in France in 1987 and the United States in 2000. It became available as a generic medication in 2019. Misoprostol was developed in 1973. The combination is on the World Health Organization's List of Essential Medicines. In the United States the medications can cost more than 500 USD as of 2023; though charities may provide for free or at low cost. While in Canada it is about 300 to 450 CAD; though is covered for Canadians. In low and middle income countries the cost ranged from 4 to 36 USD as of 2018.