User:Mr. Ibrahem/Naltrexone/bupropion

Naltrexone/bupropion, sold under the brand name Contrave among others, is a combination medication used to treat obesity together with diet and exercise. Up to 30% more people loss at least 5% body weight with use. Such use; however, is not recommended in the United Kingdom. It is taken by mouth.

Common side effects include nausea, constipation, dizziness, trouble sleeping, dry mouth, and headache. Other side effects may include suicide, psychosis, seizures, high blood pressure, and liver problems. Use during pregnancy is not recommended. It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone antidepressant.

The combination was approved for medical use in the United States in 2014, Europe in 2015, and Canada in 2018. In the United States it costs 330 USD per month as of 2021 while in Canada it is about 350 CAD as of 2022. This amount in the United Kingdom costs about £78.