User:Mr. Ibrahem/Neomycin/polymyxin B/hydrocortisone

Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. It consists of the antibiotics neomycin and polymyxin B, and the steroid hydrocortisone. It is used as an ear drop or eye drop.

The most common side effects include itchiness and a skin rash. Other side effects may include dizziness, hives, anaphylaxis, hearing loss, and headache. Safety in pregnancy and breastfeeding is unclear. The antibiotics work by killing specific types of bacteria while the steroids work by decreasing inflammation.

The combination was approved for medical use in the United States in 1964. In the United Kingdom a 10 ml bottle costs the NHS about £7.45 as of 2019. In the United States the wholesale cost of this amount is about US$50. In 2017, it was the 304th most commonly prescribed medication in the United States, with more than one million prescriptions.