User:Mr. Ibrahem/Nifurtimox

Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. In Chagas disease it is a second-line option to benznidazole. It is given by mouth.

Common side effects include abdominal pain, headache, nausea, and weight loss. There are concerns from animal studies that it may increase the risk of cancer but these concerns have not be found in human trials. Nifurtimox is not recommended in pregnancy or in those with significant kidney or liver problems. It is a type of nitrofuran.

Nifurtimox came into medication use in 1965. It is on the World Health Organization's List of Essential Medicines. It was approved for medical use in the United States in 2020. It is not available commercially in Canada. It cost about 20 USD for a course of treatment as of 2013. In regions of the world where the disease is common nifurtimox is provided for free by the World Health Organization.