User:Mr. Ibrahem/Nintedanib

Nintedanib, sold under the brand names Ofev and Vargatef, is a medication used to treat idiopathic pulmonary fibrosis and a type of non-small-cell lung cancer (NSCLC). It is specifically used for adenocarcinoma NSCLC that is advanced. It is taken by mouth.

Common side effects include abdominal pain, vomiting, liver inflammation, headache, and diarrhea. Other side effects may include blood clots, bleeding, aneurysm, and gastrointestinal perforation. Use during pregnancy may harm the baby. It is a tyrosine-kinase inhibitor which blocks vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and platelet derived growth factor (PDGF).

Nintedanib was approved for medical use in the United States and Europe in 2014. In the United Kingdom it costs the NHS about £2,200 a month as of 2021. This amount in the United States is about 12,000 USD per month.