User:Mr. Ibrahem/Norethisterone

Norethisterone, also known as norethindrone and sold under many brand names, is a progestin medication used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. This includes for endometriosis, dysfunctional uterine bleeding, and painful periods. It is used by mouth or, as norethisterone enantate, by injection into muscle. It is available in both low-dose and high-dose formulations and both alone and in combination with an estrogen.

Common side effects include menstrual irregularities, headaches, nausea, and breast tenderness. Other side effects may include depression, acne, increased hair growth. It may be used as birth control when breastfeeding. It is a manufactured progestin which causes the endometrium to change from the proliferative phase to the secretory phase. It is sometimes referred to as a "first-generation" progestin.

Norethisterone was first made in 1951 and was one of the first progestins to be developed. It came into medical use in 1957 and was introduced in combination with an estrogen as birth control in 1963. It is on the World Health Organization's List of Essential Medicines as an alternative to medroxyprogesterone acetate. It is available as a generic medication. In the United Kingdom 90 tablets of 5 mg costs the NHS about £4 as of 2021. In the United States a month of medication costs about 9 USD. In 2018, it was the 138th most commonly prescribed medication in the United States, with more than 5million prescriptions.