User:Mr. Ibrahem/Olsalazine

Olsalazine, sold under the brand name Dipentum among others, is a medication used to treat ulcerative colitis and Crohn’s disease. It is used in people who cannot take sulfasalazine. It is taken by mouth in the form of tablet or capsule. If needed, contents of the capsule can be sprinkled on food.

Side effects are uncommon but include numbess and a fast heart beat. Other side effects may include diarrhea, nausea, heartburn, tiredness, and headache. Caution is advised in kidney problems. It is broken down into mesalazine (5-ASA) in the colon by which it acts. 5-ASA than inhibits cyclooxygenase and lipoxygenase thereby reducing prostoglandin and leukotriene production.

Olsalazine was approved for medical use in the United States in 1990. It is available as a generic medication. In the United Kingdom a months supply costs the NHS around £150 as of 2021. In the United States this amount costs about 1,600 USD.