User:Mr. Ibrahem/Omaveloxolone

Omaveloxolone, sold under the brand name Skyclarys, is a medication used to treat Friedreich's ataxia. It is used in those at least 16 years old. It is taken by mouth.

Common side effects include liver problems, headache, nausea, abdominal pain, tiredness, diarrhea, and musculoskeletal pain. Other side effects may include fluid retention or lipid abnormalities. Use in pregnancy may harm the baby. How it works is unclear; however, it appears to activate the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

Omaveloxolone was approved for medical use in the United States in 2023. It was granted orphan designation in Europe in 2018. It costs about 370,000 USD per year as of 2023 in the United States.