User:Mr. Ibrahem/Osilodrostat

Osilodrostat, sold under the brand name Isturisa, is a medication used to treat Cushing's disease when pituitary surgery is either not possible or not effective. It is taken by mouth.

Common side effects are adrenal insufficiency, headache, vomiting, tiredness, and swelling. QTc prolongation, low potassium, and high blood pressure may also occur. Safety is unclear in pregnancy and use in breastfeeding is not recommended. It works by inhibiting the enzyme 11-beta-hydroxylase which makes cortisol.

Osilodrostat was approved for medical use in Europe and the United States in 2020. In the United Kingdom a month of 10 mg twice per day costs about £6700 as of 2021. In the United States this amount costs about 32,200 USD.