User:Mr. Ibrahem/Palbociclib

Palbociclib, sold under the brand name Ibrance among others, is a medication used to treat breast cancer. Specifically it is used for hormone receptor-positive (HR+) and human epidermal growth factor receptor type 2 (HER2) negative advanced disease. It is taken by mouth.

Common side effects include hair loss, low red blood cells, diarrhea, nose bleedings, infection, rash, and vomiting. Other side effects may include liver problems, pneumonitis, and infertility. Use during pregnancy may harm the baby. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

Palbociclib was approved for medical use in the United States in 2015 and Europe in 2016. In the United Kingdom 4 weeks of medication costs the NHS about £3,000 as of 2021. This amount in the United States costs about US$13,700.