User:Mr. Ibrahem/Palifermin

Palifermin, sold under the brand name Kepivance, is a medication used to treat inflamation of the mouth caused by chemotherapy. Specifically it is used for blood cancers receiving high dose chemotherapy as part of autologous stem-cell transplantation. It is given by injection into a vein. It should not be given within 24 hours of chemotherapy.

Common side effects include joint pain, numbness, swelling, redness, and pancreas inflammation. Other concerns include increased growth of certain cancers. It is a manufactured form of keratinocyte growth factor (KGF).

Palifermin was approved for medical use in 2004. While it was approved in Europe in 2005, this approval was subsequently withdrawn. Use is not approved in Canada as of 2021. In the United States a course of six doses cost about 17,700 USD as of 2021.