User:Mr. Ibrahem/Pancuronium

Pancuronium, sold under the brand name Pavulon, is a medication used to relax muscles during general anesthesia, when a person is being ventilated, and to help with endotracheal intubation. It is given by injection into a vein. Onset is relatively slow at 2 to 3 minutes while effects can last for up to 100 minutes.

Common side effects include muscle weakness. Other side effects may include anaphylaxis and increased heart rate. Use in pregnancy appears to be safe, but is not well studied. Neostigmine or pyridostigmine may be used to reverse its affects. It is a neuromuscular blocking agent.

Pancuronium was first made in 1964 and approved for medical use in the United States in 1972. It is available as a generic medication. In the United Kingdom it costs the NHS about £5 per 4 mg as of 2021. This amount is about 3 USD in the United States. It has been used in euthanasia and during lethal injection.