User:Mr. Ibrahem/Patisiran

Patisiran, sold under the brand name Onpattro, is a medication used to treat polyneuropathy in people with hereditary transthyretin-mediated amyloidosis. It is given by gradual injection into a vein.

Common side effects include upper respiratory infection, shortness of breath, muscle spasms, joint pain, redness, and dizziness. Other side effects may include vitamin A deficiency. Safety in pregnancy is unclear; though evidence shows harm in other animals. It is a small piece of RNA that blocks the production of abnormal transthyretin.

Patisiran was approved for medical use in Europe and the United States in 2018. In the United Kingdom a single vial of 10 mg costs the NHS about £7,700 as of 2021. This amount in the United States costs about 10,000 USD.