User:Mr. Ibrahem/Pemetrexed

Pemetrexed, sold under the brand name Alimta among others, is a medication used to treat mesothelioma and non-small cell lung cancer (NSCLC). It is used for mesothelioma which involves the pleura and cannot be removed by surgery. It is given by gradual injection into a vein.

Common side effects include fever, infection, inflammation of the mouth, rash, nausea, tiredness, shortness of breath, and chest pain. Other side effects may include bone marrow suppression. Use in pregnancy may harm the baby. It works by blocking the creation of DNA and RNA by inhibiting thymidylate transferase.

Pemetrexed was approved for medical use in the United States and Europe in 2004. It is available as a generic medication. In the United Kingdom 500 mg costs the NHS about £450 as of 2021. This amount in the United States is about 3,700 USD.