User:Mr. Ibrahem/Perphenazine

Perphenazine, sold under the brand name Trilafon among others, is a medication used to treat psychosis including in schizophrenia, anxiety, and nausea. Benefits appear similar to other antipsychotics. Use for behavioral problems in people with intellectual disability has not be proven useful. It is taken by mouth.

Common side effects include parkinsonism, which may include tardive dyskinesia, sleepiness, dry mouth, blurry vision, weight gain, and milk production. Other side effects may include an increased risk of death in the elderly with dementia, neuroleptic malignant syndrome, low blood pressure, seizures, and anaphylaxis. Use in pregnancy may harm the baby. It is a typical antipsychotic of the phenothiazine class.

Perphenazine was approved for medical use in the United States in 1957. In the United States 90 tablets of 4 mg costs about 33 USD as of 2021.