User:Mr. Ibrahem/Pfizer–BioNTech COVID-19 vaccine

Pfizer–BioNTech COVID-19 vaccine, known by the generic name tozinameran and brand name Comirnaty, is a COVID-19 vaccine. It is used in people over the age of four, eleven, or fifteen years depending on the jurisdictions, to provide protection against COVID-19. It was initially found to be 95% effective. It is given as at least two doses, by injection into a muscle, at least 21 days apart.

Most side effects are mild to moderate and resolve within a few days. These may include pain at the injection site, tiredness, fever, diarrhea, headache, and muscle pains. Rare side effects may include anaphylaxis, facial palsy, pericarditis, and myocarditis. There is no evidence of harm with use in pregnancy. It is an mRNA vaccine, composed of nucleoside-modified mRNA (modRNA) encoding the spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles.

The vaccine received emergency use authorization (EUA) in the United States in October 2020 and was approved for medical use in Europe in December 2020. It received full approval in the United States in August 2021. It has been authorized for use at some level in at least 151 countries as of 2022. It was initially being sold to governments for between 15 and 25 USD per dose. It was developed by the German company BioNTech and American company Pfizer. It was the first COVID‑19 vaccine to be authorized by a stringent regulatory authority. , more than 1.5billion doses have been shipped worldwide.