User:Mr. Ibrahem/Pitolisant

Pitolisant, sold under the brand name Wakix among others, is a medication for the treatment of excessive daytime sleepiness in narcolepsy. It is taken by mouth once a day in the morning.

Common side effects include headache, trouble sleeping, nausea, and anxiety. Other side effects may include QT prolongation. Safety in pregnancy is unclear. It bring about an opposite to usual response at the histamine 3 (H3) receptor. This increases the activity of histamine neurons in the brain, which keeps a person awake.

Pitolisant was approved for medical use in the United States in 2019 and Europe in 2021. In the United Kingdom it costs the NHS about £310 per month as of 2021. In the United States this amount costs about 6,800 USD.