User:Mr. Ibrahem/Plecanatide

Plecanatide, sold under the brand name Trulance, is a medication used to treat chronic idiopathic constipation (CIC) and constipation due to irritable bowel syndrome. It is taken by mouth.

Common side effects include diarrhea. Use is not recommended in children. Safety in pregnancy is unclear. It works by activating guanylate cyclase-C which increases release of chloride and bicarbonate into the intestines.

Plecanatide was approved for medical use in the United States in 2017. In the United States it costs about 470 USD per month.