User:Mr. Ibrahem/Plerixafor

Plerixafor, sold under the brand name Mozobil, is a medication used to stimulate release of stem cells from the bone marrow into the blood to be collected for later transplanted back. It is used together with a granulocyte-colony stimulating factor (G-CSF). It is given by injection under the skin.

Common side effects include diarrhea, nausea, and pain at the site of injection. Other side effects may include low platelets, splenic rupture, and release of leukemia cells into the blood. Use in pregnancy may harm the baby. It works by blocking the activity of the CXCR4 chemokine receptor.

Plerixafor was approved for medical use in the United States in 2008 and Europe in 2009. In the United Kingdom a vial of 24 mg costs the NHS about £4,900 as of 2021. In the United States this amount costs about 9,300 USD.