User:Mr. Ibrahem/Posaconazole

Posaconazole, sold under the brand names Noxafil among others, is an antifungal medication use to treat and prevent thrush, aspergillosis, mucormycosis, coccidioidomycosis, fusariosis, and chromoblastomycosis. It is used when other treatments are not appropriate. It is taken by mouth of given by injection into a vein.

Common side effects include nausea, diarrhea, fever, and liver problems. Other side effects may include allergic reactions and QT prolongation. Safety is unclear in pregnancy, with use not recommended in early pregnancy. It is in the azole family of medications and works by blocking lanosterol 14 alpha-demethylase.

Posaconazole was approved for medical use in Europe in 2005 and the United States in 2006. Generic versions have been approved. In the United Kingdom 24 tablets of 100 mg cost the NHS about £600 as of 2021. This amount in the United States costs about 410 USD.