User:Mr. Ibrahem/Potter sequence

Potter sequence is the abnormal development of a baby due to insufficient amiotic fluid during pregnancy. Symptoms include poor lung development, which results in shortness of breath and rapid breathing at birth. Other symptoms may include abnormal facial changes, clubbed feet, and bone abnormalities. Death generally occurs before or within hours of birth, though in certain cases survival may be possible.

The cause is typically insufficient amniotic fluid, known as oligohydramnios, due to kidney problems. These kidney problems may include bilateral kidney agenesis (BKA), polycystic kidney disease (autosomal dominate or recessive), kidney dysplasia, or obstruction of the ureters or pelvis of the kidneys. Other causes may include premature rupture of membranes and prune belly syndrome. Diagnosis can frequently be confirmed by ultrasound.

Often treatment involves psychological support for the family. Occasionally regular injections of saline into the uterus during pregnancy or surgery maybe an option. After birth treatment than involves management of kidney failure and poor lung development. Potter sequence affects about 1 in 2,000 to 5,000 births. Males are more commonly affected than females. The condition was first described in 1946 by Edith Potter.