User:Mr. Ibrahem/Pretomanid

Pretomanid, sold under the brand name Dovprela, is an antibiotic used to treat multi-drug-resistant tuberculosis affecting the lungs. It is generally used together with bedaquiline and linezolid. It is taken by mouth.

Common side effects include nerve damage, acne, vomiting, headache, low blood sugar, diarrhea, and liver inflammation. Other side effects may include bone marrow suppression, optic neuropathy, and QT prolongation. Safety in pregnancy is unclear. It is in the nitroimidazole class of medications.

Pretomanid was approved for medical use in the United States in 2019 and Europe in 2020. It is on the World Health Organization's List of Essential Medicines. In the developing world it cost 364 USD for 6 months in 2019. In the United States this amount costs about 3,800 USD as of 2021. It was developed by the TB Alliance.