User:Mr. Ibrahem/Probenecid

Probenecid, also sold under the brand name Probalan, is a medication primarily used to treat hyperuricemia including in gout. It is also used to decrease the clearance of β-lactam antibiotics and cidofovir. It is taken by mouth.

Common side effects include headache, vomiting, and nausea. Other side effects may include allergic reactions, kidney stones, and a worsened gout attack if started during the attack. Use in pregnancy appears to be safe, though such use has not been well studied. It works by blocking the ability of the kidney to reabsorb urate.

Probenecid was initially developed during World War II to extend penicillin supplies. It was approved for medical use in the United States in 1951 and is available as a generic medication. In the United States 100 tablets of 500 mg costs about 78 USD as of 2021.