User:Mr. Ibrahem/Quinupristin/dalfopristin

Quinupristin/dalfopristin, sold under the brand name Synercid, is a combination of two antibiotics used to treat infections by staphylococci, including Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VRE). It is not very effective against VRE. It is given by gradual injection into a vein.

Common side effects include pain at the site of injection, nausea, diarrhea, joint and muscle pain, headache, and rash. Other side effects may include Clostridioides difficile infection and anaphylaxis. Quinupristin and dalfopristin are both streptogramin antibiotics, made from from pristinamycin.

The combination was approved for medical use in the United States in 1999. In the United States 10 doses of 350 mg/150 mg costs about 4,900 USD as of 2021. In the United Kingdom it is no longer available as of 2018.