User:Mr. Ibrahem/Recombinant factor IX

Recombinant factor IX, also known as nonacog alfa among others, is a medication used to treat haemophilia B. Specifically it is used to treat and prevent bleeding. Its use improves quality of life. It is given by slow injection into a vein.

Common side effects include fever, cough, pain at the site of injection, and nausea. It may also result in allergic reactions including angioedema, hives, wheezing, or low blood pressure. Antibodies that block its ability to work may also develop. It is a manufactured version of the blood clotting enzyme factor IX, made by recombinant methods.

Recombinant versions were approved for medical use in the United States and Europe in 1997. It is on the World Health Organization's List of Essential Medicines. In the United Kingdom 1,000 units costs the NHS about £600 as of 2023. This amount in the United States costs about 1,600 USD. There are also versions made from human plasma, but these are associated with risks of infection.