User:Mr. Ibrahem/Renal cortical necrosis

Renal cortical necrosis (RCN) is the death of the outer part of the kidney. Symptoms can include decreased urine volume, flank pain, and dark brown urine. Complications can include acute kidney injury.

The cause may include sepsis, hemolytic-uremic syndrome, dehydration, preeclampsia, rejection of a transplanted kidney, and certain toxin. The underlying mechanism often involves injury to the arterioles of the kidneys as a result of low blood pressure. Diagnosis can be confirmed by medical imaging or kidney biopsy.

Treatment involves addressing the underlying cause and supportive care. This may involve intravenous fluids, antibiotics, or dialysis. Often long term dialysis or a kidney transplant is required. The one year risk of death is greater than 20%. Renal cortical necrosis is rare. About 10% of cases occur in children.