User:Mr. Ibrahem/Roflumilast

Roflumilast, sold under the trade name Daxas among others, is a medication used for the long term management of chronic obstructive pulmonary disease (COPD). It is used in those with severe disease. It is taken by mouth.

Common side effects include diarrhea, nausea, headache, back pain, trouble sleeping, and dizziness. Other side effects can include suicide. It is a selective inhibitor of the enzyme phosphodiesterase-4 (PDE-4) and works by decreasing lung inflammation.

Roflumilast was approved for medical use in Europe in 2010 and the United States in 2011. In the United Kingdom it costs the NHS about £38 per month as of 2021. This amount in the United States costs about 430 USD.