User:Mr. Ibrahem/Safinamide

Safinamide, sold under the brand name Xadago among others, is a medication used as an add-on treatment for Parkinson's disease with off episodes. Specifically it is used together with levodopa-carbidopa. It is taken by mouth.

Common side effects include trouble sleeping, difficulty controlling movements, sleepiness, dizziness, headache, cataracts, and low blood pressure with standing. Other side effects may include high blood pressure, serotonin syndrome, sudden onset of sleep, an urge to gamble, and hallucinations. is an inhibitor of monoamine oxidase B and therefore increases levels of dopamine.

Safinamide was approved for medical use in Europe in 2015, the United States in 2017, and Canada in 2019. In the United Kingdom a month of medication costs the NHS about £70 as of 2021. In the United States this amount costs about 1,000 USD.