User:Mr. Ibrahem/Sebelipase alfa

Sebelipase alfa, sold under the brand name Kanuma, is a medication used to treat lysosomal acid lipase deficiency (LAL-D). Benefit is clearest in Wolman disease. It is given by injection into a vein.

Common side effects include headache, fever, throat pain, nausea, and constipation. Other side effects may include allergic reactions. It is a recombinant form of the lysosomal acid lipase (LAL) enzyme, which helps to break down lipids.

Sebelipase alfa was approved for medical use in Europe and the United States in 2015. In Canada it cost about 892,000 CAD for an adult per year in 2018. In the United States this amount costs about 970,000 USD per year as of 2021. Its use was rejected by the United Kingdom in 2017.