User:Mr. Ibrahem/Sevoflurane

Sevoflurane, sold under the brand name Sevorane, among others, is an inhalational anaesthetic used to begin and maintain general anesthesia. Onset is rapid with a fast recovery. It can be used instead of propofol to begin anesthesia.

Safety is good. Side effects may include cough, nausea, increased saliva, and QT prolongation. It does not irritate the lungs, and therefore may be used safely in people with reactive airway disease. Rare cases of liver problems have occurred. It should not be used in people at risk of malignant hyperthermia. It may be used safely when breastfeeding.

Sevoflurane was first made in the 1960s by Ross Terrell and has been in use in Japan since 1990. It was approved for medical use in the United States in 1995. It is on the World Health Organization's List of Essential Medicines. As of 2005 it was more expensive than isoflurane or desflurane in the United States. In the United Kingdom a 250 ml container costs the NHS £123 as of 2023.