User:Mr. Ibrahem/Sodium phenylacetate/sodium benzoate

Sodium phenylacetate/sodium benzoate, sold under the brand name Ammonul among others, is a combination medication used to treat high blood ammonia that results in encephalopathy. It is used for conditions were there is problems with the enzymes involved in the urea cycle. It is given via a central venous catheter.

Common side effects include vomiting, high blood sugar, low potassium, seizures, and confusion. Other side effects may include metabolic acidosis, fluid overload, and skin necrosis. It is a combination of sodium phenylacetate and sodium benzoate. It works by binding to nitrogen.

The combination was approved for medical use in the United States in 1987. In the United States 50 ml of 10% solution of each component costs about 48,000 USD as of 2021. In Europe it was given an orphan designation in 2019.