User:Mr. Ibrahem/Talazoparib

Talazoparib, sold under the brand name Talzenna, is a medication used to treat metastatic or advanced breast cancer with BRCA mutation. It is generally used when other treatments are no longer working or suitable. It is taken by mouth.

Common side effects include tiredness, low red blood cells, nausea, low white blood cells, and low platelets. Other severe side effects may include myelodysplastic syndrome. Use during pregnancy may harm the baby. Lower doses may be used in people with kidney problems. It is a poly ADP ribose polymerase (PARP) inhibitor and works by blocking DNA repair.

Talazoparib was approved for medical use in the United States in 2018 and in Europe in 2019. In the United States a typical doses costs about 16,000 USD per month as of 2021. This amount in the United Kingdom costs the NHS about £5,000.