User:Mr. Ibrahem/Teniposide

Teniposide, sold under the brand name Vumon, is a chemotherapy medication used to treat acute lymphocytic leukemia (ALL) in children. It is a second line agent for this use. Other uses may include small cell lung cancer and lymphoma. It is given by injection into a vein.

Common side effects include low white blood cells, low red blood cells, low platelets, inflammation in the mouth, nausea, hair loss, bleeding, fever, and allergic reactions. Other side effects may include other cancers, tissue death at the site of injection, and low blood pressure. Use in pregnancy may harm the baby. It is in a class of drugs known as podophyllotoxin derivatives and is believed to work by interfering with the production of DNA.

Teniposide was approved for medical use in the United States in 1992. It has been sold in Europe since 1967 and Canada since 1984. In the United States it costs about 2,100 USD per 50 mg dose as of 2021. It is no longer commercially available in Canada.