User:Mr. Ibrahem/Teriflunomide

Teriflunomide, sold under the brand name Aubagio, is a medication used to treat multiple sclerosis (MS); specifically relapsing-remitting MS. In Scotland it is used as a second line treatment to interferon beta and glatiramer. It is taken by mouth.

Common side effects include headache, diarrhea, liver problems, nausea, and hair loss. Other side effects may include liver failure, peripheral neuropathy, and interstitial lung disease. Use in the two years before or during pregnancy may harm the baby. It is a pyrimidine synthesis inhibitor. While how it works is not entirely clear, it is believed to decrease the number of lymphocytes. It is the active metabolite of leflunomide.

Teriflunomide was approved for medical use in the United States in 2012 and and Europe 2013. In the United Kingdom it costs the NHS about 1,100 pounds per month. This amount in the United States costs about 8,400 USD as of 2021.