User:Mr. Ibrahem/Tolcapone

Tolcapone, sold under the brand name Tasmar, is a medication used to treat Parkinson's disease (PD). It is taken together with levodopa/carbidopa. It is taken by mouth. If people do not see improvement within 3 weeks it should be stopped.

Common side effects include nausea, loss of appetite, movement disorders, headache, increased dreams, and confusion. Other side effects may include liver problems, which can be severe, and psychosis. It is an inhibitor of catechol-O-methyltransferase (COMT).

Tolcapone was approved for medical use in Europe in 1997 and the United States in 1998. It is available as a generic medication. In the United Kingdom 100 tablets of 100 mg costs the NHS about £95 in 2021. This amount in the United States costs about 1,200 USD. It is not commonly used due to side effects.