User:Mr. Ibrahem/Trilaciclib

Trilaciclib, sold under the brand name Cosela, is a medication used to reduce chemotherapy-induced bone marrow suppression. Specifically it is used before platinum and etoposide or topotecan treatment for small cell lung cancer. It is given by injection into a vein.

Common side effects include tiredness, low calcium, low potassium, low phosphate, headache, and pneumonia. Other side effects may include allergic reactions, pain at the site of injection, and pneumonitis. Use in pregnancy may harm the baby. It works by temporarily blocking CDK4 and CDK6.

Trilaciclib was approved for medical use in the United States in 2021. It is not available in Europe or the United Kingdom as of 2022. In the United States it costs about 1,600 USD for 300 mg as of 2022.