User:Mr. Ibrahem/Trimethobenzamide

Trimethobenzamide, sold under the brand name Tigan among others, is a medication used to treat nausea and vomiting. This includes that due to surgery and gastroenteritis. It is taken by mouth or by injection into a muscle. Onset occurs within 40 minutes and lasts up to 4 hours.

Common side effects include blurry vision, sleepiness, and muscle cramps. Other side effects may include liver problems and allergic reactions. Safety in pregnancy and breastfeeding is unclear. Use in children with viral infections is not recommended due to concerns of Reye syndrome. It is an antihistamine and believed to work by blocking the chemoreceptor trigger zone.

Trimethobenzamide was approved for medical use in the United States in 1974. It is available as a generic medication. In the United States 30 doses cost less than 20 USD as of 2021.