User:Mr. Ibrahem/Varenicline

Varenicline, sold under the trade name Champix among others, is a medication used help people stop smoking. It is the recommended initial treatment together with behavioral support. It helps one of every 11 people who smoke, stop for at least six months. Varenicline is taken by mouth.

Common side effects include unusual dreams, nausea, and constipation. Serious side effects may include depression, anxiety, seeing or hearing things that others do not, allergic reactions, thoughts of suicide, and seizures. There is no clear harm from use in human pregnancy but such use has not been well studied and there may be harm in pregnancy in other animals. It works by binding to a type of nicotinic acetylcholine receptors in the brain, decreasing the ability of nicotine to attach, and thus reducing the desire to smoke.

Varenicline was approved for medical use in the United States and Europe in 2006. It is on the World Health Organization's List of Essential Medicines. As of 2020 it costs about 440 USD in the United States for the first month (7.60 USD per tablet). In the United Kingdom this amount is about 55 pounds. It may become avaliable as a generic medication in the US in 2020.