User:Mr. Ibrahem/Vasopressin

Vasopressin, sold under the brand name Argipressin among others, is a medication used for shock not responding to fluid resuscitation or norepinephrine. Other uses include cardiac arrest, diabetes insipidus, paralytic ileus, and gastrointestinal bleeding. It may also be used as part of a number of medical tests. It is given by injection. Onset of effects is rapid with the maximum effect at 15 min.

Common side effects include stomach ache, world spinning, flatulence, headache, or tremor. Other side effects may include a slow heart rate, mesenteric ischemia, water intoxication, and coronary ischemia. During the later part of pregnancy it may result in contraction of the uterus. It works by activating the vasopressin receptor resulting in contraction of blood vessels. In the kidneys in results in concentration of the urine.

Vasopressin was first isolated by Vincent du Vigneaud in 1953 and manufactured in 1958. It is available as a generic medication. In the United Kingdom a vial of 20 units costs the NHS about £80 as of 2020. This amount in the United States costs about 60 USD.