User:Mr. Ibrahem/Vemurafenib

Vemurafenib, sold under the brand name Zelboraf, is a medication used to treat certain types of late-stage melanoma and Erdheim-Chester disease. Specifically it is used in those with a BRAF V600E mutation. It is taken by mouth.

Common side effects include joint pain, hair loss, itchiness, QT prolongation, and tiredness. Other side effects may include Dupuytren contracture, sensitivity to radiation therapy, eye inflammation, liver problems, and a new cancer. Use in pregnancy may harm the baby. It works by blocking the b-Raf enzyme.

Vemurafenib was approved for medical use in the United States in 2011 and Europe in 2012. In the United Kingdom 56 tablets of 240 mg costs the NHS about £1,750 as of 2021. This amount in the United States costs about 2,650 USD.